Research and projectsResearch groups at IBA MU

Research groups at IBA MU Cancer Epidemiology

Leader of the research group Leader of the research group: Jan Mužík, Ph.D.

The group of Cancer Epidemiology at the Institute of Biostatistics and Analyses evaluates long-term epidemiological data of all cancer types in the Czech Republic.


Leader of the research group:

Jan Mužík, Ph.D.

Jan Mužík, Ph.D.

Contact: muzik@iba.muni.cz

Evaluation of cancer epidemiology is a very important activity of the Institute of Biostatistics and Analyses. Cancer incidence rates are high in all economically developed countries, and the Czech Republic is no exception in this respect. In some cancer types, the Czech population even ranks among the most afflicted countries worldwide. Tens of thousands of new cancer patients are diagnosed in the Czech Republic each year, and there are hundreds of thousands of cancer patients who were diagnosed, treated and followed-up in previous years. Under these circumstances, the analysis of information on cancer patients is of strategic importance, and is a very important part of planning the costs of cancer care in the Czech Republic. Cancer epidemiology plays a key role in both retrospective and prospective analyses (let us mention Predictions of Cancer Burden, Health Technology Assessment and Evaluation of Cancer Screening Programmes, for example).

For this purpose, the Czech oncology is well equipped with unique, long-term, and population-based data on malignant tumours. A consolidated collection of demographic data is available in the Czech Republic, and the Czech National Cancer Registry (CNCR) has been maintained since 1976, covering 100% of all cancer diagnoses and the entire Czech population. The existence of data itself, albeit in high quality, is not enough. This data needs to be processed, analysed and adequately used.

The group of Cancer Epidemiology at the Institute of Biostatistics and Analyses has rich experience with the evaluation of large datasets of epidemiological data. Its outputs are utilised by the Czech Society for Oncology, health care payers, and many other subjects.

Selected projects

System for Visualization of Oncology Data (SVOD)

  • This research project, which is run under the auspices of the Board of the Czech Society for Oncology, has led to the development of a comprehensive information portal focusing on cancer epidemiology in the Czech Republic. Its objective is to provide access to valuable data on Czech cancer patients to a wide spectrum of users from the Czech Republic as well as from abroad (for this reason, the portal has also its English version). The web portal represents a dynamic information platform, which is regularly updated and which lets the user perform a number of analyses according to their own choice. All analyses published this way contain safe and publishable data about the cancer epidemiology and do not contain any personal data of patients.
    http://www.svod.cz

Uroweb

  • Detailed information regarding the epidemiology of urological malignancies, interactive software tools for both analysis and visualisation of epidemiological data. Users can examine epidemiological analyses of urological cancers on both regional and national level, and to make a comparison with international data.
    http://www.uroweb.cz

Selected publications

  • Dušek L, Mužík J, Malúšková D, Májek O, Pavlík T, Koptíková J, Melichar B, Büchler T, Fínek J, Cibula D, Babjuk M, Svoboda M, Vyzula R, Ryška A, Ryska M, Petera J, Abrahámová J. Cancer incidence and mortality in the Czech Republic. Klinická onkologie 2014, 27(6): 406–423. doi: 10.14735/amko2014406.
  • Pavlík T, Májek O, Büchler T, Vyzula R, Petera J, Ryska M, Ryška A, Cibula D, Babjuk M, Abrahámová J, Vorlíček J, Mužík J, Dušek L. Trends in stage-specific population-based survival of cancer patients in the Czech Republic in the period 2000-2008. Cancer Epidemiology 2014, 38(1): 28–34. doi: 10.1016/j.canep.2013.11.002.
  • Ondrušová M, Mužík J, Durdík S, Ondruš D. Long-term trends in the development of the epidemiology of breast cancer in the Slovak and Czech Republic with reference to applied screening and international comparisons. Neoplasma 2012, 59(1): 70–78. doi: 10.4149/neo_2012_009.
  • Ondrušová M, Mužík J, Huňáková L, Belohorská B, Tomek D, Ondruš D, Kavcová E. Trends in the lung cancer incidence and mortality in the Slovak and Czech Republics in the contexts of an international comparison. Clinical and Translational Oncology 2012, 14(9): 659–666. doi: 10.1007/s12094-012-0850-y.
  • Dušek L, Abrahámová J, Bortlíček Z, Brabec P, Fínek J, Gregor J, Hoch J, Klimeš D, Koptíková J, Kožený P, Májek O, Malúšková D, Mužík J, Pavlík T, Poc P, Ryska M, Seifert B, Slavíček L, Suchánek Š, Tomášek J, Vorlíček J, Vyzula R. Epidemiologie, prevence a léčba kolorektálního karcinomu dle dostupných českých a mezinárodních dat, 2012. ISBN 978-80-87347-07-2: 204. (on-line)
  • Dušek L, Mužík J, Pavlík T, Májek O, Koptíková J. Epidemiologie zhoubných nádorů trávicího traktu v České republice - současný stav a predikce, Gastroenterologie a hepatologie 2012, 66 (5): 331-339.
  • Ondrušová M, Mužík J, Hrčka R, Friedová L, Ondruš D. Do we know the cause of the highest colorectal cancer incidence, the changes in the mortality trends and the clinical stages in the Slovak and Czech Republic, the representatives of the Central European region? Neoplasma 2011, 58(4): 283–290. doi: 10.4149/neo_2011_04_283.
  • Dušek L, Mužík J, Gelnarová E, Fínek J, Vyzula R, Abrahámová J. Incidence a mortalita nádorových onemocnění v České republice, Klinická onkologie 2010, 23 (5): 311-324. (on-line)
  • Dušek L, Mužík J, Abrahámová J, Pavlík T, Májek O, Koptíková J, Vyzula R, Fínek J, Vorlíček J. Epidemiologie solidních nádorů v ČR podle dat Národního onkologického registru za období 1977-2007, Postgraduální medicína 2010, 12 (3): 268-277. (on-line)
  • Dušek L, Májek O, Pavlík T, Vyzula R, Abrahámová J, Fínek J, Mužík J, Koptíková J, Brabec P, Kožený P, Daneš J, Ryška A, Vorlíček J. Nová data pro plánování a optimalizaci léčebné péče o pacientky s karcinomem prsu v České republice v období 2010–2011. Farmakoterapie 2010, 6: 1801–1209. (on-line)

 


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