Research and projectsResearch groups at IBA MU

Research groups at IBA MU Health Technology Assessment

Leader of the research group Leader of the research group: Jiří Jarkovský, Ph.D.

The group of Health Technology Assessment at the Institute of Biostatistics and Analyses contributes to the introduction of processes focused on a comprehensive assessment of quality and cost-effectiveness of health care, the so-called Health Technology Assessment.

Leader of the research group:

Jiří Jarkovský, Ph.D.

Jiří Jarkovský, Ph.D.


The group participates in numerous projects aiming to provide a comprehensive information service for health care facilities, which focuses on patient characteristics, migration, treatment burden and treatment outcomes, and makes it possible to compare these indicators with an overall benchmarking of other health care facilities in the area or nationwide.

The technical solution developed at IBA MU makes it possible to interconnect various available (yet underused) information sources from individual health care facilities, and to work with them using a uniform parametric structure. Data obtained in this manner can be employed to answer questions often asked by health care facility management and physicians, which up to now could not be clearly answered because data was only available in partial data sources. Oncology is currently the most developed medical specialty in this regard, interconnecting administrative data from hospitals, data from the Czech National Cancer Registry, and data from the Death Records Database of the Czech Republic. Typical outputs include a summary overview of cancer patients and their treatment in health care facilities, their clinical and geographic migration, employment and results of care provided by specialised centres, or specialised outputs focused on specific diagnoses and/or treatment modalities. However, the proposed technical solution can be generally applied to other medical specialties, and analyses can be thus performed for practically all diagnostic groups.

Selected projects


  • The PET/CT-CZ(Q) aims to provide exact and representative data for the area of planning and optimisation of capacity of PET/CT scans in individual regions of the Czech Republic. In this special field of medicine, the project aims to establish a data background which would be sustainable in the long term, and which could be updated easily. Mapping of performed PET/CT scans, their indications and validated predictions of expectable numbers of future scans might provide rational materials which would be essential to plan for this area of health care. As PET/CT scans are predominantly indicated for cancer patients, oncology represents the main area of planned analyses. However, the project also envisages to process clinical data on all diagnostic groups with the indication of PET/CT scan. The project design is based on processing of previously obtained (i.e., existing) data. More specifically, this is data in the Czech National Cancer Registry as the population-wide source of data, as well as representative data from the clinical practice, which is generated by processing administrative data from major health care facilities.

Proposal of performance indicators in health care

  • Usability of interconnected data from projects focused on the evaluation of health care quality and outcomes is common for all projects, and each of them can contribute to the proposal of performance indicators. Typical examples involve the evaluation of patient survival, length of treatment, time to treatment initiation, timely availability of health care, or a detailed analysis of employment and effectiveness of treatment provided by specialised centres. Evaluation of treatment standards, such as the adherence to a sequence and continuity of treatment procedures, compliance to treatment modalities, or occurrence of treatment complications, can also be performed.

Analysis of cancer treatment burden in health care facilities

  • Outcomes of this project characterise the cancer treatment burden of involved health care facilities; the analysis is based on the interconnection of administrative data from health care facilities and data from the Czech National Cancer Registry. A well-arranged report analyses the structure of patient diagnoses, their basic demographic and clinical characteristics, and time trends in their incidence and prevalence rates. A special attention is dedicated to the patient structure in terms of their passage through health care facilities from both the geographic and clinical point of view. Treatment outcomes are described by a survival analysis standardised to patients’ age, sex, and disease stage at the time of diagnosis. Results of individual health care facilities are supplemented with a comparison to a benchmark database of comprehensive cancer centres (CCCs).

Analysis of cancer treatment provided by specialised centres and its outcomes

  • This report extends a standard analysis of cancer burden of a given health care facility by a detailed analysis of treatment of solid tumours and haemato-oncological malignancies that is provided by specialised centres. Additionally, the report provides a summary of molecules employed in the centre’s treatment, their routes of administration and dates of administration. Individual health care facilities are further characterised by overall numbers of treated patients according to cancer types, by the incidence and prevalence of treated patients and their time trends, and by the predicted numbers of patients to be treated in future. The treated patients are described by their demographic and clinical typologies, migration, and treatment outcomes in terms of overall survival and treatment duration.

Selected publications

  • Blaha M, Janča D, Klika P, Mužík J, Dušek L.: Project I-COP - Architecture of Software Tool for Decision Support in Oncology. Studies in Health Technology and Informatics 2013; 186: 130–134.