Research and projectsResearch groups at IBA MU

Research groups at IBA MU Research of Emerging Infectious Diseases (EID)

Leader of the research group Leader of the research group: Natália Martínková, Ph.D.

The group of Research of Emerging Infectious Diseases at the Institute of Biostatistics and Analyses investigates pathogen and host interactions from the perspective of their evolution.


Leader of the research group:

Natália Martínková, Ph.D.

Natália Martínková, Ph.D.

Contact: martinkova@ivb.cz

The EID group focuses on multidisciplinary approaches with strong emphasis on international cooperation. The research includes:

  • analysis of adaptive trait evolution both on phenotypic and genomic levels, such as detection of horizontal gene transfer, natural selection or host switching modelling, or phylogenetic representation
  • pathogen and host distribution modeling,
  • pathogen phylogeography on temporal scale.

Projects

Bat adaptations to the fungal disease geomycosis

  • White-nose syndrome is an emerging fungal infection that drastically reduced bat populations in North America, leading to increased costs of insect control in agriculture and public health. Research of differentially resilient populations might inform management decisions in bat conservation as well as reveal biomechanisms of tolerance of fungal infections.

Selected publications

  • Zukal J, Bandouchova H, Bartonicka T, Berkova H, Brack V, Brichta J, Dolinay M, Jaron KS, Kovacova V, Kovarik M, Martinkova N, Ondracek K, Rehak Z, Turner GG, Pikula J. White-nose syndrome fungus: a generalist pathogen of hibernating bats. PLoS One 2014, 9(5): e97224. doi: 10.1371/journal.pone.0097224.
  • Jaron KS, Moravec JC, Martínková N. SigHunt: horizontal gene transfer finder optimized for eukaryotic genomes. Bioinformatics 2014, 8: 1081–1086. doi: 10.1093/bioinformatics/btt727.
  • Irwin NR, Bayerlova M, Missa O, Martinkova N. Complex patterns of host switching in New World arenaviruses. Mol Ecol 2012, 21(16): 4137–4150. doi: 10.1111/j.1365-294X.2012.05663.x.

 


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