Research and projectsGrant projects

Grant projects Interaction between pulse pressure, pulse wave velocity, augmentation index, natriuretic peptides and echocardiography and their predictive value in acute heart failure

Coordinator Coordinator: Dušek Ladislav

Duration Duration: 2009–2011

Prognosis establishment is a crucial point for the optimisation of acute heart failure (AHF) management. The aim of the project was to evaluate the most important non-invasive prognostic parameters and to create a model combining these parameters in order to identify patients at risk of an unfavourable development of the condition.

The research found that significant non-invasive prognostic factors of an acute decompensation of pre-existing chronic heart failure involve B-type natriuretic peptide (BNP), maximum level of cardiac troponin T (cTnT), left ventricular mass index (LVMI), left atrial volume and calculated glomerular filtration rate. The results of the research were published in five articles in peer-reviewed journals.

  • Funding: The project was supported by the Ministry of Health of the Czech Republic within the programme “Departmental Programme of Research and Development – MH II from 2008 to 2011”. The project is registered with the identifier NS10422.
  • Brief overview of results: you can find more detailed information – in Czech language only – in the VaVaI information system