List of all projects DIOS - Dose Intensity as Oncology Standard(FRVS No. 2608/2007)
Coordinator: Klimeš Daniel
Start projektu: 2006
Contracting authority: Czech Society for Oncology
This project develops an electronic library of chemotherapy regimens, which can be used for educational purposes as well as in the clinical practice.
The DIOS project was launched in 2006 with the primary objective to enhance the oncologists' awareness of the significance of dose intensity monitoring in anticancer chemotherapy. Another objective was to develop a fully electronic version of chemotherapy regimens which could complement the Principles of Cytostatic Therapy in Malignant Tumours, published by the Czech Society for Oncology of CMA JEP. The advantages of the electronic version include easy updates, as well as the possibility of direct use for clinical practice and/or educational purposes. The electronic standards can also be used as templates for hospital information system databases .
Several partial tasks had to be resolved in order to achieve the goals mentioned above, the most important of them being the survey and digitization of current chemotherapy regimens. Furthermore, the project objectives assumed that the resulting electronic version would be continuously updated and available to all potential users at any time. For these reasons, the Library of Chemotherapy Regimens is developed as an on-line freely available portal which contains educational materials and software applications, apart from the library itself.
At the present time, the database contains more than 250 definitions of chemotherapy regimens for all significant cancer diagnoses. With regard to its contents, the DIOS portal can be helpful not only to oncologists, but also to students of medicine who are interested in anticancer therapy. The Library of Chemotherapy Regimens is equipped with a search engine which facilitates the search of regimens according to selected criteria, such as diagnosis, treatment intent, treatment line or a specific cytostatic. Furthermore, the application suggests a treatment plan with user-specified number of cycles for a given patient. The calculation of cytostatic doses is explained in detail, and information is provided on the significance of dose intensity. Dose intensity can be calculated for chemotherapy regimen(s) of user's choice, using the on-line calculator on DIOS portal.
- Citation: KLIMEŠ, Daniel, DUŠEK, Ladislav, FÍNEK, Jindřich, KUBÁSEK, Miroslav, KOPTÍKOVÁ, Jana, ŠNAJDROVÁ, Lenka, BRABEC, Petr, NOVOTNÝ, Jan, VYZULA, Rostislav, ABRAHÁMOVÁ, Jitka, PETRUŽELKA, Luboš. Electronic Library of Chemotherapy Regimens and its portal solution. DIOS Project: Dose Intensity as Oncology Standard /verze 1.0/ [online]. Masaryk University [2005]. On-line available: http://dios.registry.cz. ISSN 1802-887X
- Funding: AMGEN Ltd.
- Number of records: 260 (as on 30 March 2012)
- Brief overview of results: you can find more detailed information on the website of the DIOS project
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